
Tetrahedron p. 4687 - 4712 (1992)
Update date:2022-08-02
Topics:
Pichon, Clotilde
Clemens, Karen R.
Jacobson, Alan R.
Scott, A. Ian
Three new derivatives of porphobilinogen (PBG; 1) were designed and synthesized to study the mechanism of ammonia loss during the tetramerization of PBG, catalyzed by the PBG deaminase.Two of these compounds are substituted at the C-11 carbon with CH3 or
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