Journal of Pharmaceutical Sciences p. 365 - 366 (1992)
Update date:2022-07-29
Topics:
Nargund
Badiger
Yarnal
Ten new substituted 2-mercapto-3-(N-aryl)pyrimido[5,4-c]cinnolin-4-(3H)- ones (4) were prepared by refluxing substituted 4-aminocinnolin-3-carboxylic acid (3) with substituted arylisothiocyanate in anhydrous pyridine. These derivatives were evaluated for their antimicrobial and anti-inflammatory activities. Some of the title compounds possess potent antimicrobial activity.
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