Two effective procedures for the synthesis of trichloromethyl ketones, useful precursors of chiral α-amino and α-hydroxy acids

DOI: 10.1016/S0040-4039(00)92656-X

Source and publish data:

Tetrahedron Letters p. 3435 - 3438 (1992)

Update date:2022-08-02

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Authors:

Corey Corey

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Shao Shao

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Article abstract of DOI:10.1016/S0040-4039(00)92656-X

Trichloroacetic acid can be converted to trichloromethyl ketones in good yield by two practical new procedures, one involving the catalyzed reaction of trichloroacetic acid with aldehydes at 23°C followed by oxidation and the other utilizing the coupling

Full text of DOI:10.1016/S0040-4039(00)92656-X

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