4(3H)-Quinazolinones from the reaction of N-arylnitrilium salts with isocyanates

DOI: 10.1055/s-1992-26203

Source and publish data:

Synthesis p. 697 - 701 (1992)

Update date:2022-07-30

Topics:

Authors:

Al-Talib

Jochims Jochims

Hamed Hamed

Wang Wang

Ismail Ismail

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1992-26203

N-Arylnitrilium salts 1 react with isocyanates 2 to give salts 3 of 4(3H)-quinazolinones 4, from which compounds 4 can be obtained with base. A metathesis of an isocyanate with a nitrilium salt is reported.

Full text of DOI:10.1055/s-1992-26203

Products guided by the article

Product name:4(3H)-Quinazolinone, 6-chloro-2-(4-chlorophenyl)-3-methyl-

Cas No:143582-49-4

R&D Labs maybe for 143582-49-4

Hubei Danao Pharmaceutical Co.,Ltd.

website:http://www.danaopharm.com

Contact:+86-719-5251167

Address:Fandan Road,Danjiangkou,Hubei
Chen jie

Contact:027-87677569

Address:Room 2203, yujingmingmen Buidling One, xiongchu Road, wuhan city, hubei province, China
Shanghai Dianyang Industry Co.,ltd

Contact:+86 21 6492 4669

Address:Chejing RD, Songjiang District, Shanghai, China
Suzhou CarbonWell Pharma-Tech Co., Ltd

Contact:Tel: + 86 (0)512-8898-1216; + 86-18606258602

Address:2358 Changan Road, Wujiang Scientific Innovation Park, Wujiang, Jiangsu Province, P. R. China 215200
Jiangsu Willing Bio-Tech Co ltd

website:http://www.willingbio.com/

Contact:+86 18796908173

Address:No 18 Guoqiao Road

Relevant to this article

Discovery of potent, selective, bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model, Part I: Transformation of selective pyrazolodiazepinone phosphodiesterase 4 (PDE4) inhibitors into selective PDE2 inhibitors

Doi:10.1016/j.bmcl.2013.03.072
(2013)
2-Amino-4-trimethylsilyl-γ-butyrolacton - ein silylanaloges Homothreonin-Lacton

Doi:10.1002/prac.19923340411
(1992)
Symmetric and unsymmetric 3,3′-linked bispyrroles via ring-enlargement reactions of furan-derived donor-acceptor cyclopropanes

Doi:10.1039/c3ob40228b
(2013)
Atropisomerism in a Molecular Gear, 8-Bromo-1,4-dimethyl-9-(2-methylbenzyl)triptycene

Doi:10.1246/cl.1990.1373
(1990)
Synthesis and in vitro biological evaluation of nitric oxide-releasing derivatives of hydroxylcinnamic acids as anti-tumor agents

Doi:10.1016/j.cclet.2013.03.006
(2013)
Propargyl hydrazides: Synthesis and conversion into pyrazoles through hydroamination

Doi:10.1002/chem.201202828
(2012)

Article Doi