Research on Chemical Intermediates p. 7307 - 7318 (2017)
Update date:2022-08-03
Topics:
Zhang, Yizong
Zhang, Zhuan
Chen, Yang
Li, Yiqun
Ethylenediamine functionalized poly(vinyl chloride) (PVC–EDA) was conveniently synthesized by treatment of commercially available PVC powder with ethylenediamine solution. This amine-functionalized PVC was subsequently immersed in copper sulfate solution to form the supported copper catalyst [PVC–EDA–Cu(II)]. The as-prepared catalyst was well characterized with FT–IR, SEM, DSC, TGA, and ICP methods. It was found to catalyze efficiently the CuAAC reaction for the regioselective synthesis of 1,4-disubstituted-1,2,3-triazoles from benzyl halides, phenylacetylenes, and sodium azide in the presence of sodium ascorbate in water to give the corresponding products under mild and environmentally benign conditions. Various benzyl halides containing electron-withdrawing groups and electron-donating groups afforded the desired products in up to 98% yield. The present procedure has the merits of short reaction time and simple reaction work-up. Moreover, this catalyst can be recovered by simple filtration and reused for at least five consecutive runs without any loss of its catalytic activity.
View MoreChengdu Shengnuo Biological Technology Co., Ltd.
Contact:86-028-85275045
Address:Sichuan Province Chengdu hi tech Zone Tianfu Avenue North of 1480
website:http://www.angchenchem.com
Contact:+86-510-88302099 82327577
Address:Rm. 404/405, Floor 4th, No. 983 FengXiang Road, Wuxi, China
Contact:+86+21-58956006 15800617331
Address:402 Room, 150# Cailun Road, Zhangjiang high tech park, Shanghai
Zhejiang Haizhou Pharmaceutical Co., Ltd.
website:https://www.haizhoupharma.com/
Contact:+86-576-88221016
Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Contact:86-0555-5136566
Address:Maanshan city, He county Anhui province high-tech zone No.8 Laoxiahe east road
Doi:10.1016/S0040-4020(01)90360-6
(1992)Doi:10.1016/S0040-4039(00)61222-4
(1992)Doi:10.1271/bbb.69.1861
(2005)Doi:10.1021/jacs.8b10212
(2019)Doi:10.1021/ja00052a072
(1992)Doi:10.1016/j.bmc.2015.05.011
(2015)