Regioselective Introduction of Carbon-3 Substituents to 5-Alkyl-7-methoxy-2-phenylbenzofurans: Synthesis of a Novel Adenosine A1 Receptor Ligand and Its Derivatives

DOI: 10.1021/jo00052a046

Source and publish data:

Journal of Organic Chemistry p. 7248 - 7257 (1992)

Update date:2022-09-26

Topics:

Authors:

Yang, Zhen

Liu, Han Biao

Lee, Chi Ming

Chang, Hson Mou

Wong, Henry N. C.

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Article abstract of DOI:10.1021/jo00052a046

By maintaining the balance between the electronic requirements, the stereochemical restrictions as well as the kinetic and thermodynamic factors, the unprecedented regioselective electrophilic aromatic substitution of formyl and nitro groups to carbon-3 o

Full text of DOI:10.1021/jo00052a046

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