MedChemComm
Concise Article
These experiments will guide the synthesis of focused libraries 14 E. Miranda, I. K. Nordgren, A. L. Male, C. E. Lawrence,
of analogues of 5b and 5c to further understand and validate the
SAR for the compounds reported in this study.
F. Hoakwie, F. Cuda, W. Court, K. R. Fox, P. A. Townsend,
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Acknowledgements
Cancer Research UK is acknowledged for providing nancial 16 A. L. Kung, S. D. Zabludoff, D. S. France, S. J. Freedman,
support for these studies (C180/A9327 to D.E.T.), and the Alger-
ian Government is thanked for providing a studentship (to Y.B.).
E. A. Tanner, A. Vieira, S. Cornell-Kennon, J. Lee, B. Wang,
J. Wang, K. Memmert, H.-U. Naegeli, F. Petersen, M. J. Eck,
K. W. Bair, A. W. Wood and D. M. Livingston, Cancer Cell,
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