A convenient synthesis of 2-(F-alkyl)-4-hydroxyquinolines

DOI: 10.1016/S0022-1139(00)83977-9

Source and publish data:

Journal of Fluorine Chemistry p. 209 - 214 (1994)

Update date:2022-08-04

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Authors:

Huang, Wei-Yuan

Liu, Yan-Song

Lu, Long

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Article abstract of DOI:10.1016/S0022-1139(00)83977-9

A convenient new route to 2-(F-alkyl)-4-hydroxyquinolines has been developed.In the presence of triethylamine, treatment of ethyl 2,2-dihydropolyfluoroalkanoates with aromatic amines in acetonitrile at 70 deg C led to a mixture of the corresponding enamin

Full text of DOI:10.1016/S0022-1139(00)83977-9

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