Tetrahedron p. 9939 - 9950 (1992)
Update date:2022-08-03
Topics:
Banerjee
Trivedi
The synthesis of a steroidal spin label 10 containing a tempo nitroxide group in the side chain of lithocholic acid 1 is reported. This is the first report of a tempo nitroxide in a steroidal side chain. The methodology involved a Wittig condensation between the steroidal phosphonium ylide 7 and tempone 9. The synthesis of a proxyl nitroxide 16 with the proxyl group in the side chain of 1 is also described. A mild oxidation of 16 to the corresponding 3-keto spin label 17 in high yield is also achieved.
View Morewebsite:http://www.oceanchem-group.com
Contact:86-536-8596048
Address:9th floor,Building B future Plaza, No.88.Fenghuang Street,Weifang,Shandong,China
Shanghai Forever Synthesis Co.,Ltd.
Contact:021-61124658
Address:Zhoukang Road,Pudong New District,Shanghai,China
Tianjin Emulsion Science&Technology Development Co.,Ltd
Contact:13901380442
Address:Vake Garden New Town New Yi Bai Road Beichen District Tianjin,China
Shanghai KFSL Pharmaceutical Technology Co.,Ltd.
Contact:+86-21-39971718
Address:859 jiadingchengliu shanghai
Hangzhou Gangjin Chemical Co.,Ltd.(expird)
Contact:+86-571-85109780
Address:707 Zhejiang Minhang Bldg., No.290 Zhongshan North Road, Hangzhou 310003, China
Doi:10.1016/0968-0896(95)00174-3
(1996)Doi:10.1039/c3cc44952a
(2013)Doi:10.1016/j.molliq.2020.112722
(2020)Doi:10.1002/chem.201302455
(2014)Doi:10.1021/jo01287a054
(1967)Doi:10.1039/c3cc45469j
(2013)
