New applications of the Mitsunobu reaction in the synthesis of C-2 N-methyl carbapenems

DOI: 10.1016/S0040-4039(00)60855-9

Source and publish data:

Tetrahedron Letters p. 7133 - 7136 (1992)

Update date:2022-09-26

Topics:

Authors:

Arnould Arnould

Landier Landier

Pasquet Pasquet

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)60855-9

N-acyl amides and N-acylamino heterocycles can be reacted regioselectively with C-2 hydroxymethyl carbapenems under Mitsunobu conditions:synthesis of amides, exocyclic alkylation of amino heterocycles and transformation into 2-aminomethyl carbapenems are

Full text of DOI:10.1016/S0040-4039(00)60855-9

Products guided by the article

Product name:(4S,5R,6S)-6-((R)-1-Hydroxy-ethyl)-3-[(1H-imidazol-2-ylamino)-methyl]-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Cas No:145663-72-5

R&D Labs maybe for 145663-72-5

Jiangxi Global Natural Spice Co., Ltd.

website:https://www.jxhqxl.com/

Contact:+86-796-8106598

Address:No.89, Wenshan Road,South Industrial Park, Jishui County,Jiangxi Province
Zhuhai Rundu Pharmaceutical co.,Ltd

Contact:+86-756-7630755

Address:No.6,North Airport Road,Sanzao Town,Jinwan District
Shanghai Bojing Chemical Co., Ltd.

Contact:021-37122233

Address:6F Buildiing 11,No.388,Baifu Road,District Fengxian.Shanghai, China.
Chuzhou Baiao Biologhy S&T Co., Ltd.

Contact:+86-25-83212599；+86-25-83212699 13705185959

Address:Room 905, Tianzheng International Platza, No.399, Zhongyang Road ,Nanjing, Jiangsu Province, China
Beijing Pure Chem Co.,Ltd.

Contact:+86-10-83993285

Address:Rm.1708, Haobai Tower, Building 6, No.50, North Road, West Third Ring, Haidian District, Beijing, China

Relevant to this article

Chiral NCN pincer rhodium(III) complexes with bis(imidazolinyl)phenyl ligands: Synthesis and enantioselective catalytic alkynylation of trifluoropyruvates with terminal alkynes

Doi:10.1002/adsc.201200967
(2013)
Synthesis and Antiviral Activity of 1-Cyclobutyl-5-(2-bromovinyl)uracil Nucleoside Analogues and Related Compounds

Doi:10.1021/jm00088a015
(1992)
Displacement Stereochemistry and Product-Formation Selectivities in the Solvolysis of Cyclooctyl p-Bromobenzenesulfonate

Doi:10.1021/ja00365a036
(1982)
Cholecystokinin dipeptoid antagonists: Design, synthesis, and anxiolytic profile of some novel CCK-A and CCK-B selective and 'mixed' CCK-A/CCK-B antagonists

Doi:10.1021/jm00057a005
(1993)
Synthesis and biological activity of 3-substituted isoxazolecarboxamides

Doi:10.1007/s00706-010-0265-9
(2010)
Synthesis and structure-affinity relationships of selective high-affinity 5-HT₄ receptor antagonists: Application to the design of new potential single photon emission computed tomography tracers

Doi:10.1021/jm300943r
(2012)

Article Doi