
Tetrahedron p. 9841 - 9868 (1992)
Update date:2022-08-03
Topics:
Coutrot, Ph.
Grison, C.
Charbonnier-Gerardin, C.
A general route to phosphopeptides with a 2-oxoalkylphosphonate moiety at the terminal N-amino group or with a 1-aminoalkylphosphonate moiety at the terminal C-carboxyl group is described.The method allows the preparation of various phosphopeptides with an α-alkylated carbon atom on the P-C bond from the very available dialkylpohosphonoalcanoic acids as starting products.
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(1992)