Total Synthesis of the Second Messenger Analogue D-myo-Inositol 1- Phosphorothioate 4,5-Biphosphate: Optical Resolution of DL-1-O-Allyl-2,3,6-tri-O-Benzyl-myo-inositol and Fluorescent Labelling of myo-Inositol 1,4,5-Triphposphate

DOI: 10.1039/P19920002899

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 2899 - 2906 (1992)

Update date:2022-08-02

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Authors:

Lampe, Dethard

Mills, Stephen J.

Potter, Barry V. L.

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Article abstract of DOI:10.1039/P19920002899

Two routes for the synthesis of the myo-inositol 1,4,5-triphosphate analogue myo-inositol 1-phosphorothioate 4,5-bisphosphate have been devised.DL-2,3,6-Tri-O-benzyl-1-O-(cis-prop-1-enyl)-myo-inositol was prepared from DL-1-O-allyl-2,3,6-tri-O-benzyl-myo-

Full text of DOI:10.1039/P19920002899

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