SYNTHESIS OF (+/-)-2'-OXA-CARBOCYCLIC-2',3'-DIDEOXYNUCLEOSIDES AS POTENTIAL ANTI-HIV AGENTS

DOI: 10.1016/0040-4039(91)80873-5

Source and publish data:

Tetrahedron Letters p. 271 - 274 (1991)

Update date:2022-07-30

Topics:

Authors:

Bamford, Mark J.

Humber, David C.

Storer, Richard

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(91)80873-5

Novel 2',3'-dideoxynucleosides, having the pentofuranosyl oxygen at the 2'-position, were obtained by a short synthetic route from diethyl malonate and bromoacetalehyde dimethyl acetal.The results of biological testing against HIV-1 in vitro are presented.

Full text of DOI:10.1016/0040-4039(91)80873-5

Products guided by the article

Product name:2-Amino-9-((2R,4S)-4-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one

Cas No:146609-09-8

R&D Labs maybe for 146609-09-8

Sichuan JieYao Co., Ltd.

Contact:+86-838-5655598

Address:Guanghan Nanfeng Industrial Zone
MENGNA

Contact:18698110882

Address:1303 No2 building,LuoMa Garden,YongAn Road,Hexi District,Tianjin city
GLD peptide scientific lnc.

Contact:21-7631221 15884421033

Address:326 Science and technology,Shanghai,China
SuZhou Hua-Emy Chemical Import and Export Co., LTD.

Contact:+86-512-88804994; +86-512-88804550;

Address:710, Building B, International Trade Center, 12 Huanghelu, Changshu, Jiangsu,China
Shanghai AoBo Bio-Pharmaceutical Technology Co., Ltd.

Contact:+86-21-51320130-801, 816

Address:Room 601, No. 1011, Halei Road, Zhangjiang High-Tech Park, Pudong, Shanghai

Relevant to this article

Redox-Neutral Synthesis of Selenoesters by Oxyarylation of Selenoalkynes under Mild Conditions

Doi:10.1021/acs.orglett.8b02544
(2018)
Two- and Four-Carbon Homologation of Aldehyde by AgClO4-Catalyzed Addition of Alkoxyalkenylzirconocene Chloride

Doi:10.1016/S0040-4039(00)60583-X
(1993)
Synthesis of (R)-(+)-patulolide A

Doi:10.1055/s-1993-25820
(1993)
INDOLE DERIVATIVES. 138. SYNTHESIS OF α-(5-INDOLYL)ETHYLAMINE AND 5-(2-AMINOETHOXY)- AND 5-(AMINOETHYLTHIO)TRYPTAMINES

Doi:10.1007/BF00529476
(1992)
Diorganotin(IV) derivatives of N-methyl p-fluorobenzo-hydroxamic acid: Preparation, spectral characterization, X-ray diffraction studies and antitumor activity

Doi:10.3390/molecules18078696
(2013)
The adenosine A_2A antagonistic properties of selected C8-substituted xanthines

Doi:10.1016/j.bioorg.2013.06.006
(2013)

Article Doi