Synthesis of potential inhibitors of hemagglutination by influenza virus: Chemoenzymic preparation of N-5 analogs of N-acetylneuraminic acid

DOI: 10.1016/S0040-4020(01)80502-0

Source and publish data:

Tetrahedron p. 1 - 12 (1993)

Update date:2022-08-04

Topics: Biological testing Purification and characterization Structure-Activity Relationship (SAR) Studies Scale-up and Production Enzymatic Reaction Conditions

Authors:

Sparks, Michelle A.

Williams, Kevin W.

Lukacs, Christine

Schrell, Andreas

Priebe, Gregory

Spaltenstein, Andreas

Whitesides, George M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)80502-0

A chemoenzymic route to neuraminic acid 2 is described. This method is based on conversion of N-carbobenzoxymannosamine (ManCBz) 3 to N-carbobenzoxyneuraminic acid (Neu5CBz) 4, catalyzed by Neu5Ac aldolase. The Neu5CBz 4 was converted to the α-methyl glyc

Full text of DOI:10.1016/S0040-4020(01)80502-0

Products guided by the article

Product name:4,7,8,9-tetra-O-acetyl-5-N-carbobenzoxylamino-2-β-chloro-2,3,5-trideoxy-β-D-glycero-D-galacto-2-nonulopyranosidonic acid methyl ester

Cas No:146669-05-8

R&D Labs maybe for 146669-05-8

Shandong Dayi Chemical Co., Ltd.

website:http://www.dayi.com.cn

Contact:+86- 535-7388728. 15306386031

Address:No 1 Danya west road, Laiyang City, Shandong province
Shenzhen Hongyuan Import & Export Co., Ltd.

Contact:0755-26407171

Address:Shenzhen Hongyuan Chemical New Materials Technology Co., Ltd.
Zhuhai Rundu Pharmaceutical co.,Ltd

Contact:+86-756-7630755

Address:No.6,North Airport Road,Sanzao Town,Jinwan District
HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Contact:+86-186-02659358

Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
Taizhou Elitechemie MediPharma Technology Co.,Ltd.

Contact:+86-523-86810021

Address:Building G14,NO.1 Avenue,China Medical City, Taizhou, Jiangsu,China

Relevant to this article

Synthesis of a hybrid molecule containing neocarzinostatin chromophore analogue and minor groove binder

Doi:10.1016/S0040-4039(00)61648-9
(1993)
A Stereoselective Synthesis of Trisubstituted Alkenes. Part 1. Nickel-catalysed Coupling of Grignard Reagents with 5-Alkyl-2,3-dihydrofurans

Doi:10.1039/P19920003419
(1992)
The quantitative surface analysis of an antioxidant additive in a lubricant oil matrix by desorption electrospray ionization mass spectrometry

Doi:10.1002/rcm.6690
(2013)
Doi:10.1021/ja00986a019
(1967)
Synthetic receptors for CG base pairs.

Doi:10.1021/ol006157d
(2000)
Reaction of electron-deficient N-sulfinylanilines with chiral α-hydroxy acids: A new process for the synthesis of enantiomerically pure α-hydroxy amides

Doi:10.1016/S0040-4039(00)01011-X
(2000)

Article Doi