Synthetic Applications of Bis(iminophosphoranes). One-Pot Preparation of Rigid Bicyclic Guanidines

Article abstract of DOI:10.1021/jo00059a015

A one-pot synthesis of <6 + 6>, <6 + 7>, and <6 + 8> bicyclic guanidines based on a new method of dihydropyrimido annelation, which involves reaction of bis(iminophosphoranes) with aryl isocyanates or isothiocyanates is described.The method is also applic