
Tetrahedron p. 1063 - 1070 (1993)
Update date:2022-08-03
Topics:
Warmerdam, Erwin G. J. C.
Brussee, Johannes
Kruse, Chris G.
Van Der Gen, Arne
Optically active (R)-cyanohydrins have been transformed into cyanohydrin esters of opposite configuration under Mitsunobu conditions and subsequently solvolyzed to (S)-cyanohydrins in high chemical and optical yield. The method works well for allylic and
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