An expedient approach to the diphenyl ether cross-linked amino acids of glycopeptide antibiotics

Article abstract of DOI:10.1016/0040-4039(93)85035-U

Displacement reactions of 2,6-dibromobenzoquinone with phenoxides and subsequent elaboration of 5 into the aryl amino acid of model C,D,E-ring segment of vancomycin have been described.