Tetrahedron p. 2751 - 2760 (1993)
Update date:2022-08-04
Topics:
Kasturi, Tirumalai R.
Mandal, Asish B.
Sumana, Bangalore G.
Rajasekhar, Betagiri
Reaction of 2-bromomethyl-1-(2'-tetrahydropyranyloxy)benzene 3a with tetrachlorocatechol (TCC) in acetone in presence of anhydrous K2CO3 resulted in the formation of diastereomeric products to which cis- and trans- 6-chloro-8-hydroxy-8-(2-oxopropyl)spiro<9H-benzoxanthen-9,2'(1'H)benzofuran>-7(8H)-one (7a and 8a) structures were assigned, along with tetrachlorocatechol ethers (5a and 6a).Similar reaction of 3a with tetrabromocatechol (TBC) gave the expected monobromo compounds 7d and 8d along with the ethers 5d and 6d.When the reaction was repeated with substrates 3b-c with TCC/TBC in ketonic solvents (acetone/methyl ethyl ketone), the corresponding compounds 5b-c to 8b-c, 5e-f to 6e-f, 7e-g and 8e-h were obtained.A suitable explanation has been given for the formation of acetonyl compound 6 in this reaction.
View MoreContact:18669908765
Address:Zibo City, Shandong Province, P.R.China
Shanghai better-in Medical Technology Co.,LTD.
Contact:+86-21-38921049
Address:Lane 720 zhangjianggaoke cailun road, Pudong, Shanghai, room 513
Shandong Jiulong Hisince Pharmaceutical Co.,Ltd.
Contact:+86-15853188990
Address:Huadian Pioneer Park, Huadian Township, Qihe County, Dezhou City, Shandong, P.R.China
Hefei TNJ chemical industry co.,ltd
website:https://www.tnjchem.com
Contact:+86-551-65418695
Address:B911 Xincheng Business Center, Qianshan Road, Hefei Anhui China
Suzhou Jingye Medicine & Chemical Co., Ltd
website:http://www.jingyechem.cn
Contact:+86-512-66658588
Address:No. 88, Sanlian Street, Jinfeng Road, Suzhou New District, Jiangsu Province, P. R. China
Doi:10.1021/om990467m
(1999)Doi:10.1016/j.tetlet.2019.07.001
(2019)Doi:10.1016/S0040-4039(01)80892-3
(1985)Doi:10.1080/00397911.2018.1502783
(2018)Doi:10.1021/ja01105a054
(1953)Doi:10.1007/BF00512808
(1983)