ELECTROPHILIC QUENCHING OF DIANIONS OF 4--1,4-DIHYDROPYRIDINES. A DIRECT ROUTE TO FUNCTIONALIZED HANTZSCH ESTERS

DOI: 10.1016/S0040-4039(00)77500-9

Source and publish data:

Tetrahedron Letters p. 1099 - 1102 (1993)

Update date:2022-08-06

Topics:

Authors:

Balasubramaniam, T. N.

Natale, N. R.

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Article abstract of DOI:10.1016/S0040-4039(00)77500-9

An expedient entry into the preparation of Hantzsch Esters is presented.The method involves dilithiation and selective electrophilic quenching of 4-<5'-sulfonylmethylisoxazoyl>-1,4-dihydropyridines.Key words: isoxazole - 1,4-dihydropyridine - phenylsulfonyl - metalation

Full text of DOI:10.1016/S0040-4039(00)77500-9

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