Mercaptoacyl matrix metalloproteinase inhibitors: The effect of substitution at the mercaptoacyl moiety

DOI: 10.1016/S0960-894X(97)10069-5

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2765 - 2770 (1997)

Update date:2022-08-04

Topics:

Authors:

Baxter, Andrew D.

Bhogal, Ranjev

Bird, John B.

Buckley, George M.

Gregory, David S.

Hedger, Paul C.

Manallack, David T.

Massil, Tracy

Minton, Kevin J.

Montana, John G.

Neidle, Stephen

Owen, David A.

Watson, Robert J.

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Article abstract of DOI:10.1016/S0960-894X(97)10069-5

The in vitro potency of orally-active mercaptoacyl matrix metalloproteinase inhibitors is increased by the introduction of appropriate substitutents on the mercaptoacyl moiety.

Full text of DOI:10.1016/S0960-894X(97)10069-5

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