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Synthesis and some conformational features of the 5'-deoxy-5'-methylphosphonate linked dimer, 5'-deoxy-5'-C-(phosphonomethyl)thymidin-3'-yl (thymidin-5'-yl)methylphosphonate [p(CH2)Tp(CH2)T]

DOI: 10.1016/0040-4020(95)00131-Q

Source and publish data:

Tetrahedron p. 4145 - 4160 (1995)

Update date:2022-08-02

Topics:

Authors:

SzaboSzabo

StawinskiStawinski

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Article abstract of DOI:10.1016/0040-4020(95)00131-Q

Efficient synthesis of the 5'-deoxy-5'-methylphosphonate linked thymidine dimer 11 [p(CH2)Tp(CH2)T] was developed via the 5'-deoxy-5'-C-(phosphonomethyl)-3'-silylated thymidine derivative 4 as a key intermediate. Conformational analy

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Full text of DOI:10.1016/0040-4020(95)00131-Q

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