Azulene derivatives as TXA2/PGH2 receptor antagonists - II. Synthesis and biological activity of 6-mono- and 6-dihydroxylated-isopropylazulenes

DOI: 10.1016/0968-0896(96)00038-7

Source and publish data:

Bioorganic and Medicinal Chemistry p. 575 - 591 (1996)

Update date:2022-07-30

Topics:

Authors:

Yokota, Masayuki

Uchibori, Satoko

Hayashi, Hiromi

Koyama, Rei

Kosakai, Kazuhiro

Wakabayashi, Shuichi

Tomiyama, Tsuyoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0968-0896(96)00038-7

In order to examine the correlation between activity and hydrophilicity of the side chain of sodium 3-[4-(4-chlorobenzenesulfonylamino)butyl]-6- isopropylazulene-1-sulfonate (KT2-962), a non-prostanoid TXA₂/PGH₂ receptor antagonist,

Full text of DOI:10.1016/0968-0896(96)00038-7

Products guided by the article

Product name:3-(4-Benzenesulfonylamino-butyl)-6-isopropyl-azulene-1-sulfonic acid butyl ester

Cas No:150094-27-2

R&D Labs maybe for 150094-27-2

Shanghai Mintchem Development ., Ltd

Contact:0086 21 5190 8570

Address:R602,4#,89Nong, Mudan Road Pudong Shanghai China
Tianjin Crest Pharmaceutical R&D Co., Ltd. （Tianjin Yao Technology Development Co., Ltd.）(expird)

Contact:+86-22-66211386

Address:Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457
Sinoway Industrial Co., Ltd.

website:http://www.china-sinoway.com

Contact:+86-592-5853819

Address:16/F,Huicheng Comm,Complex,No839 XiaHe Rd, Xiamen,China
HAINAN JINYING IMPORT AND EXPORT CO. LTD

Contact:+86-898-32875423

Address:A SECTION 19TH FL, TIMES SQUARE, NO.2 GUO MAO AVENUE HAIKOU, HAINAN, P. R. OF CHINA
Shanghai Korey Pharm Co.,Ltd.(expird)

Contact:021-61840961 021-61840962

Address:No.157,Zhuguang Rd, Qingpu, Shanghai, China

Relevant to this article

A - And B -fluorinated aminophosphonates-Synthesis and properties

Doi:10.1080/10426507.2015.1091832
(2016)
A series of penicillin derived C2-symmetric inhibitors of HIV-1 proteinase: synthesis, mode of interaction, and structure-activity relationships.

Doi:10.1021/jm00073a011
(1993)
Graphene oxide: An efficient and reusable carbocatalyst for aza-Michael addition of amines to activated alkenes

Doi:10.1039/c1cc15230k
(2011)
Direct detection of S-palmitoylation by mass spectrometry

Doi:10.1021/ac402850s
(2013)
Borole derivatives X. Syntheses of (η⁵-borole)metal complexes via borole ammonia adducts. Complexes of the chromium group metals and the crystal and molecular structures of tetracarbonyl <η⁵-(1-phenylborole)>chromium and its molybden

Doi:10.1016/0022-328X(87)87155-3
(1987)
Oxoammonium Salts. 5. A New Synthesis of Hindered Piperidines Leading to Unsymmetrical TEMPO-Type Nitroxides. Synthesis and Enantioselective Oxidations with Chiral Nitroxides and Chiral Oxoammonium Salts

Doi:10.1021/jo00070a018
(1993)

Article Doi