Azulene derivatives as TXA2/PGH2 receptor antagonists - II. Synthesis and biological activity of 6-mono- and 6-dihydroxylated-isopropylazulenes

DOI: 10.1016/0968-0896(96)00038-7

Source and publish data:

Bioorganic and Medicinal Chemistry p. 575 - 591 (1996)

Update date:2022-07-30

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Authors:

Yokota, Masayuki

Uchibori, Satoko

Hayashi, Hiromi

Koyama, Rei

Kosakai, Kazuhiro

Wakabayashi, Shuichi

Tomiyama, Tsuyoshi

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Article abstract of DOI:10.1016/0968-0896(96)00038-7

In order to examine the correlation between activity and hydrophilicity of the side chain of sodium 3-[4-(4-chlorobenzenesulfonylamino)butyl]-6- isopropylazulene-1-sulfonate (KT2-962), a non-prostanoid TXA₂/PGH₂ receptor antagonist,

Full text of DOI:10.1016/0968-0896(96)00038-7

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Product name:3-(4-Benzenesulfonylamino-butyl)-6-isopropyl-azulene-1-sulfonic acid butyl ester

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