
Tetrahedron Letters p. 6525 - 6528 (1993)
Update date:2022-09-26
Topics:
Fink
Strupczewski
An efficient three step procedure for the preparation of 6-fluoro-1,2-benzisothiazoles is described. The key step is a regioselective nucleophilic aromatic substitution reaction in which the carbonyl group of a ketone or aldehyde directs nucleophilic disp
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