Organic Letters p. 2793 - 2795 (2016)
Update date:2022-08-04
Topics:
Wright, Austin C.
Haley, Christopher K.
Lapointe, Guillaume
Stoltz, Brian M.
An insertion of arenes into both imides and anhydrides via reactive aryne intermediates is presented. The reaction is performed under exceptionally mild conditions, and the corresponding ketoamide products are amenable to derivatization to deliver a variety of synthetically useful motifs such as quinolones, indoles, and ketoanilines.
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