Asymmetric Conjugate Additions of Chiral Allyl- and Crotylphosphonamide Anions to α,β-Unsaturated Carbonyl Compounds: Highly Stereocontrolled Access to Vicinally Substituted Carbon Centers and Chemically Asymmetrized Chirons

Article abstract of DOI:10.1021/jo00071a004

Reactions of anions derived from chiral nonracemic allyl and crotyl bicyclic phosphonamides with α,β-unsaturated cyclic ketones, esters, lactones, and lactams take place at the γ-position of the reagents and lead to diastereomerically pure or highly enric