Tetrahedron p. 6375 - 6380 (1993)
Update date:2022-07-30
Topics:
Aitken, David J.
Guillaume, Dominique
Husson, Henri-Philippe
The first asymmetric synthesis of the naturally-occurring cyclopropane amino acid carnosadine, 1, has been carried out. Starting from the previously available chiral intermediate 2, appropriate amine protection and side-chain modifications permitted introduction of the key guanidyl substituent in a short and efficient synthesis to give the title compound in five steps and 45% overall yield.
View MoreLuoyang Aoda chemical Co.,Ltd.
Contact:+86-379-67518785 67516588
Address:MiaoWan industry district,YanShi City,Henan,China
Sichuan Sangao Biochemical Co., Ltd
Contact:+86-28-84874233
Address:19F, Bldg.2, Shudu Center, Tianfu 2nd St., Hi-tech zone, Chengdu 610041, Sichuan Province, China.
Contact:13357117572
Address:No.149 Shiji dadao Road.
Contact:021-36356756
Address:Room601,Building No.14,280 Yangcheng Road,Shanghai
Zhejiang Genebest Pharmaceutical Co.,Ltd.
Contact:0086-571-63532866
Address:No.1 Jinboshi Rd Lishan Town Fuyang City Zhejiang Province China
Doi:10.1021/ol403447g
(2014)Doi:10.1021/jo00075a065
(1993)Doi:10.1016/S0968-0896(03)00219-0
(2003)Doi:10.1248/cpb.41.861
(1993)Doi:10.1248/cpb.41.1255
(1993)Doi:10.1021/nl500378k
(2014)