Further studies of the structure-activity relationships of 1-[1-(2- benzo[b]thienyl)cyclohexyl]piperidine. Synthesis and evaluation of 1-(2- benzo[b]thienyl)-N,N-dialkylcyclohexylamines at dopamine uptake and phencyclidine binding sites

Article abstract of DOI:10.1021/jm00077a011

We previously reported (J. Med. Chem. 1993, 36, 1188-1193) that changes to the ring size of the piperidine and cyclohexyl rings of the high-affinity and selective dopamine (DA)-uptake inhibitor 1-[1-(2- benzo[b]thienyl)cyclohexyl]piperidine (BTCP, 2) caus