Substituted chromenes as potent, orally active 5-lipoxygenase inhibitors

DOI: 10.1021/jm00075a013

Source and publish data:

Journal of Medicinal Chemistry p. 3580 - 3594 (1993)

Update date:2022-08-05

Topics:

Authors:

Satoh Satoh

Stanton Stanton

Hutchison

Libby Libby

Kowalski

Lee Lee

White White

Kimble Kimble

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Article abstract of DOI:10.1021/jm00075a013

A series of chromene derivatives was synthesized and evaluated for their in vitro and ex vivo 5-lipoxygenase (5-LO) inhibitory activity. These compounds were prepared by condensation of appropriate salicyl aldehydes with α,β-unsaturated carbonyl compounds

Full text of DOI:10.1021/jm00075a013

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