Synthesis of a Novel Heterospirocyclic 3-(N-Methyl-N-phenylamino)-2H-azirine and its Use as an Amino Acid Equivalent in the Preparation of a Model Tripeptide

Article abstract of DOI:10.1016/S0040-4020(01)87199-4

The synthesis of a novel heterospirocyclic 3-amino-2H-azirine based on the reaction between amide enolates and diphenylphosphorochloridate is described.This compound has been shown to be a useful amino acid equivalent and the synthesis of a model tripepti