Chiral precursors for the synthesis of enantiomerically pure piperidines. Total synthesis of (R)-(-)-coniine

DOI: 10.1016/S0040-4039(00)76803-1

Source and publish data:

Tetrahedron Letters p. 2223 - 2226 (1994)

Update date:2022-08-02

Topics:

Authors:

Amat, Mercedes

Llor, Nuria

Bosch, Joan

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Article abstract of DOI:10.1016/S0040-4039(00)76803-1

The preparation of chiral cis- and trans-oxazolopiperidones 1, 2, and 3 by alternative procedures and an efficient synthesis of the piperidine alkaloid (R)-(-)-coniine from trans-1 is reported.

Full text of DOI:10.1016/S0040-4039(00)76803-1

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