Synthesis of 4,4-Difluoro-L-Arginine

DOI: 10.1016/S0040-4039(00)79285-9

Source and publish data:

Tetrahedron Letters p. 7195 - 7196 (1993)

Update date:2022-08-05

Topics:

Authors:

Kim, Kyoung Soon

Qian, Ligang

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)79285-9

Preparation of 4,4-difluoro-L-arginine 1 as an L-arginine surrogate is described starting with tBoc-D-serine. pKa of guanidine moiety of 1 was found to be 11.2 compared to 13.2 of arginine guanidine group.

Full text of DOI:10.1016/S0040-4039(00)79285-9

Products guided by the article

Product name:(S)-tert-butyl 5-(benzyloxycarbonylamino)-4,4-difluoro-1-hydroxypentan-2-ylcarbamate

Cas No:153335-07-0

R&D Labs maybe for 153335-07-0

Taizhou KEDE Chemical.Co.,Ltd.

Contact:86-576-84613060

Address:Jiangkou Chemical Zoon
Jiaxing Taixin Pharmaceutical Chemical Co., Ltd

Contact:0573-82613601

Address:Chemical Park, Jiaxing, Zhejiang, China
Wuxi Morality Chemical Co., Ltd(expird)

Contact:

Address:B/7F, 321th WuYun Rd, Wanda Plaza, Wuxi City, 214174, China
Anhui Hope-Chem Co., Ltd.

Contact:86-551-63540590

Address:No 1388 Furong Rd., Hefei, Anhui, China
Shanghai Longjin Metallic Material Co., Ltd.

website:http://www.shlongjin.cn/

Contact:021-56517503,56502257

Address:No.16, Lane 555, Chengyin Road, Shanghai

Relevant to this article

Centrotriindane-and triptindane-based polymers of intrinsic microporosity

Doi:10.1016/j.polymer.2013.07.035
(2014)
Stereoselective Total Syntheses of (+/-)-Isoagatholactone and (+/-)-12α-Hydroxyspongia-13(16),14-diene, Two Marine Sponge Metabolites

Doi:10.1039/P19830000135
(1983)
Stereocontrolled syntheses of novel styryl lactones, (+)-goniodiol, (+)- goniotriol, (+)-8-acetylgoniotriol, (+)-goniofufurone, (+)-9- deoxygoniopypyrone, (+)-goniopypyrone, and (+)-altholactone from common intermediates and cytotoxicity of their congener

Doi:10.1016/S0040-4020(99)00023-X
(1999)
Cerium(III) chloride remarkably increases the rates of formation and yields of ketones in the reaction of lithium carboxylates with organolithiums

Doi:10.1016/S0040-4039(00)76511-7
(1994)
Synthesis and studies of calcium channel blocking and antioxidant activities of novel 4-pyridinium and/or N-propargyl substituted 1,4-dihydropyridine derivatives

Doi:10.1016/j.crci.2013.07.003
(2014)
Push-pull unsymmetrical substitution in nickel(II) complexes with tetradentate N2O2 Schiff base ligands: Synthesis, structures and linear-nonlinear optical studies

Doi:10.1039/c9dt01216h
(2019)

Article Doi