The synthesis of 5-hydroxy-5-methylhydantoin nucleoside and its insertion into oligodeoxyribonucleotides

DOI: 10.1016/S0040-4039(00)61462-4

Source and publish data:

Tetrahedron Letters p. 8101 - 8102 (1993)

Update date:2022-08-03

Topics:

Authors:

Guy Guy

Dubet Dubet

Teoule Teoule

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Article abstract of DOI:10.1016/S0040-4039(00)61462-4

5-hydroxy-5-methylhydantoin is a nucleobase lesion induced by the action of ionizing radiation on thymine residue in DNA. The protected nucleoside cyanoethyldiisopropylphosphoramidite has been synthesized and used to prepare chemical DNA fragments contain

Full text of DOI:10.1016/S0040-4039(00)61462-4

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