Synthesis of substituted indole-2-carboxylates: Versatile introduction of a carbamoyl moiety at the C-3 position

Article abstract of DOI:10.1080/00397919908085936

This paper deals with a novel and versatile synthetic approach for the introduction of a functionalized ethynyl side chain at the C-3 position of the 2-carboxyindole nucleus. The key step of this process is represented by the coupling reaction between the

Full text of DOI:10.1080/00397919908085936

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Synthetic Communications: An
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Synthesis of Substituted Indole-2-
carboxylates: Versatile Introduction
of a Carbamoyl Moiety at the C-3
Position
Simone A. Giacobbe a b , Romano Di Fabio a , Davide Baraldi
a , Alfredo Cugola a & Daniele Donati a
a Glaxo Wellcome S.p.A., Medicines Research Centre , Via A.
Fleming 4, I-37135, Verona, Italy
b European Patent Office , Ehrardtstrasse 27, Munich,
Germany
Published online: 17 Sep 2007.
To cite this article: Simone A. Giacobbe , Romano Di Fabio , Davide Baraldi , Alfredo Cugola
& Daniele Donati (1999) Synthesis of Substituted Indole-2-carboxylates: Versatile Introduction
of a Carbamoyl Moiety at the C-3 Position, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 29:18, 3125-3135, DOI:
10.1080/00397919908085936
To link to this article: http://dx.doi.org/10.1080/00397919908085936
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