Synthesis of new 3,5-disubstituted isoxazoles with specific anti-group B rhinovirus activity in vitro

DOI: 10.1016/0223-5234(93)90025-A

Source and publish data:

European Journal of Medicinal Chemistry p. 669 - 674 (1993)

Update date:2022-08-04

Topics:

Authors:

Mazzei Mazzei

Balbi Balbi

Sottofattori

Garzoglio

De Montis

Corrias Corrias

La Colla

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(93)90025-A

3,5-Disubstituted isoxazoles 4a-f were synthesized as potential anti-rhinovirus agents. These compounds were prepared in good yield by treatment of the corresponding 2-(dialkylamino)chromones 3a-f with hydroxylamine. Compounds 4 were demethylated to obtai

Full text of DOI:10.1016/0223-5234(93)90025-A

Products guided by the article

Product name:3-(Diethylamino)-5-(2'-hydroxy-4'-methoxyphenyl)isoxazole

Cas No:153528-45-1

R&D Labs maybe for 153528-45-1

GenicBio Limited

Contact:+86-(0)21-3770 9035

Address:Room 301, Building 2, Meijiabang Road 1508, Shanghai China
Zibo Fuxi'er Chemical Co.,Ltd （Shanxian Fuxi'er Chemical Co.,Ltd）

Contact:+86-533-2091422

Address:Eastern 4 on the 3th Road ,Liangxiang Industrial Park, Zibo city ,Shandong,China
Chuzhou Baiao Biologhy S&T Co., Ltd.

Contact:+86-25-83212599；+86-25-83212699 13705185959

Address:Room 905, Tianzheng International Platza, No.399, Zhongyang Road ,Nanjing, Jiangsu Province, China
Yixing Bluwat Chemicals Co., Ltd.

Contact:+86 510 87821568

Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
Chen jie

Contact:027-87677569

Address:Room 2203, yujingmingmen Buidling One, xiongchu Road, wuhan city, hubei province, China

Relevant to this article

Synthesis of Benzo-Fused Benzodiazepines Employed as Probes of the Agonist Pharmacophore of Benzodiazepine Receptors

Doi:10.1021/jm00032a007
(1994)
Syntheses of 5-thienyl- and 5-furyl-substituted benzodiazepines: Probes of the pharmacophore for benzodiazepine receptor agonists

Doi:10.1016/0223-5234(96)88259-6
(1995)
Catalyst-controlled wacker-type oxidation: Facile access to functionalized aldehydes

Doi:10.1021/ja411749k
(2014)
Trifluoromethyl fluorocoxib A detects cyclooxygenase-2 expression in inflammatory tissues and human tumor xenografts

Doi:10.1021/ml400485g
(2014)
Bis(N-2-propylsalicylideneamino-N,O)cobalt(II)

Doi:10.1107/S0108270196007111
(1996)
A practical and catalytic reductive olefin coupling

Doi:10.1021/ja4117632
(2014)

Article Doi