Synthesis of new 3,5-disubstituted isoxazoles with specific anti-group B rhinovirus activity in vitro

DOI: 10.1016/0223-5234(93)90025-A

Source and publish data:

European Journal of Medicinal Chemistry p. 669 - 674 (1993)

Update date:2022-08-04

Topics:

Authors:

Mazzei Mazzei

Balbi Balbi

Sottofattori

Garzoglio

De Montis

Corrias Corrias

La Colla

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Article abstract of DOI:10.1016/0223-5234(93)90025-A

3,5-Disubstituted isoxazoles 4a-f were synthesized as potential anti-rhinovirus agents. These compounds were prepared in good yield by treatment of the corresponding 2-(dialkylamino)chromones 3a-f with hydroxylamine. Compounds 4 were demethylated to obtai

Full text of DOI:10.1016/0223-5234(93)90025-A

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