Journal of Organic Chemistry p. 2935 - 2938 (1994)
Update date:2022-08-03
Topics:
Pettit
Barkoczy
Srirangam
Singh
Herald
Williams
Kantoci
Hogan
Groy
Synthesis of the dolastatin 10 (1) dipeptide segment N-(tert-butoxycarbonyl)-dolaproinyl-dolaphenine (2, Boc-Dap-Doe) and four chiral isomers (3-5, 13) has been summarized. Formation of the amide bond was readily accomplished employing diethyl cyanophosph
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