Journal of Medicinal Chemistry p. 293 - 304 (1994)
Update date:2022-07-30
Topics:
Islam, Imadul
Ng, Ka-yun
Chong, Kong Teck
McQuade, Thomas J.
Hui, John O.
et al.
The outstanding limitations to the oligopeptide as a therapeutic agent are poor oral availability and rapid biliary clearance.To address these concerns a series of eight peptidic HIV-1 protease inhibitors containing the structural segment of the vitamin b
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