Amidinoyl Isothiocyanates in the Synthesis of Condensed Heterocycles: Preparation of Quinazolino-benzotriazepines and Quinazolino-benzotetraazepines

Article abstract of DOI:10.1007/BF00817309

When heated, amidinoyl isothiocyanates (I) with 2-nitrophenyl isothiocyanate cyclize to 4-(2'-nitroanilino)quinazolines (II) and after reduction to 2'-amino derivatives (III).The latter serve as precursors to derivatives of the title compounds. - Keywords: Amidinoyl isothiocyanate, 2-morpholino, 2-piperidino; 6-Bromo-quinazolino<3,4-c><1,3,5>-benzotriazepine; Quinazolino<3,4-c><1,2,3,5>-benzotetraazepine