Synthesis of the cholesteryl ester prodrugs cholesteryl ibuprofen and cholesteryl flufenamate and their formulation into phospholipid microemulsions

DOI: 10.1002/jps.2600830907

Source and publish data:

Journal of Pharmaceutical Sciences p. 1222 - 1228 (1994)

Update date:2022-07-29

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Authors:

Murtha Murtha

Ando Ando

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Article abstract of DOI:10.1002/jps.2600830907

Phospholipid microemulsions have been suggested as a drug-delivery system for hydrophobic compounds. In this study hydrophobicity was achieved by derivatizing with cholesterol. Cholesteryl ibuprofen (3) and cholesteryl flufenamate (4) were synthesized. 3

Full text of DOI:10.1002/jps.2600830907

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