Synthesis of the cholesteryl ester prodrugs cholesteryl ibuprofen and cholesteryl flufenamate and their formulation into phospholipid microemulsions

DOI: 10.1002/jps.2600830907

Source and publish data:

Journal of Pharmaceutical Sciences p. 1222 - 1228 (1994)

Update date:2022-07-29

Topics:

Authors:

Murtha Murtha

Ando Ando

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jps.2600830907

Phospholipid microemulsions have been suggested as a drug-delivery system for hydrophobic compounds. In this study hydrophobicity was achieved by derivatizing with cholesterol. Cholesteryl ibuprofen (3) and cholesteryl flufenamate (4) were synthesized. 3

Full text of DOI:10.1002/jps.2600830907

Products guided by the article

Product name:(3beta)-cholest-5-en-3-yl 2-{[3-(trifluoromethyl)phenyl]amino}benzoate

Cas No:154394-16-8

R&D Labs maybe for 154394-16-8

JADECHEM NINGBO CO.,LTD.

Contact:+86-574-89075960

Address:#100 Xiang Yun Road, New High tech area, Ningbo, China
TC CHEMICALS CO.,LTD

Contact:0550-7041128 0550-7090578

Address:Wangdian Street,Xinjie Town
Beijing Tianjia Chemical Science & Technology Co.,Ltd

Contact:86-0550-2392698

Address:No.388, Shiliang Road (East),
Antaeus Bio-technology Co., LTD(expird)

Contact:021-31252569

Address:shanghai pudong
Zibo Xiaoguang Chemical Material Co., Ltd

Contact:15954099116

Address:Boshan Development Zone

Relevant to this article

Potential anxiolytic agents. Part 4: Novel orally-active N⁵-substituted pyrido[1,2-a]benzimidazoles with high GABA-A receptor affinity

Doi:10.1016/S0960-894X(02)00463-8
(2002)
Four-Component Reaction between Secondary Phosphines, Primary Amines, Aldehydes, and Chalcogens: A Facile Access to Functionalized α-Aminophosphine Chalcogenides

Doi:10.1055/s-0036-1588127
(2017)
Silver(I)-catalyzed aminocyclization of 2,3-butadienyl and 3,4-pentadienyl carbamates: An efficient and stereoselective synthesis of 4-vinyl-2-oxazolidinones and 4-vinyltetrahydro-2H-1,3-oxazin-2-ones

Doi:10.1246/bcsj.68.1689
(1995)
Gabapentin hybrid peptides and bioconjugates

Doi:10.1016/j.bmc.2013.12.017
(2014)
Synthesis and Diels-Alder reaction of thieno[2,3-c:4,5-c′]dipyrroles

Doi:10.1016/S0040-4020(01)80426-9
(1993)
Indole derivatives with antimycobacterial activity

Doi:10.1002/ardp.19943270209
(1994)

Article Doi