Tetrahedron Letters p. 5725 - 5728 (1984)
Update date:2022-08-04
Topics:
Joshua, Alummoottil V.
Scott, John R.
A simple and efficient method for the direct symmetrical bis-acylation of spermidine and other linear triamines using acylimidazoles is described.By this procedure, the siderophore natural product N1,N8-bis(2,3-dihydroxybenzoyl) spermidine was synthesized in an overall yield of 70percent in two steps.
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