Studies of HIV-1 protease inhibitors. II. Incorporation of four types of hydroxyethylene dipeptide isosteres at the scissile site of substrate sequences

DOI: 10.1248/cpb.41.1378

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1378 - 1386 (1993)

Update date:2022-08-05

Topics: HIV-1 Protease Inhibitors studies Incorporation

Authors:

Sakurai Sakurai

Higashida

Sugano Sugano

Nishi Nishi

Saito Saito

Ohata Ohata

Handa Handa

Komai Komai

Yagi Yagi

Nishigaki

Yabe Yabe

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.41.1378

Human immunodeficiency virus type 1 (HIV-1) protease inhibitors containing four types of hydroxyethylene dipeptide isosteres were designed and synthesized. These inhibitors consist of eight stereoisomers of phenylalanylproline (Phe-Ψ[H.E.]-Pro), four ster

Full text of DOI:10.1248/cpb.41.1378

NII-Electronic Library Service

Products guided by the article

Product name:(1S,2R,1'S,2'S)-2-(2'-tert-butoxycarbonylamino-1'-hydroxy-3'-phenylpropyl)cyclopentane-1-carboxylic acid n-butylamide

Cas No:155320-48-2

R&D Labs maybe for 155320-48-2

Changsha Easchem Co.,Limited

website:http://www.easchem.com

Contact:+86-731-89722861 89722891

Address:2/F-4/Bld Colorful Palace, No.605 Changsha Ave, Yuhua Area Changsha Hunan China.
SJZ THLD IMP & EXP CO LTD

website:http://www.truewingroup.com

Contact:86-311-66699812

Address:NO.600 ZHONGSHAN EAST ROAD SHIJIAZHUANG
Nanjing Chemipioneer Pharma&Tech Co.,Ltd

website:http://www.chemipioneer.com.cn

Contact:+86-25-52685700

Address:Room 305，A Block，Biological-Medicine Building，Business Start-up Center，Xin-ke 1st Road, High-tech development zone，Nanjing city，Jiangsu Province, China
Chengdu Pukang Biotechnology Co., Ltd

website:http://www.pu-kang.com

Contact:86-028-63976226

Address:No. 868 Xiwang Road,Xinjin county,Chengdu city, China
TC CHEMICALS CO.,LTD

Contact:0550-7041128 0550-7090578

Address:Wangdian Street,Xinjie Town

Relevant to this article

Functionalized N,N-Diphenylamines as Potent and Selective EPAC2 Inhibitors

Doi:10.1021/acsmedchemlett.5b00477
(2016)
Facile nitrosyl N-O bond cleavage upon thermolysis of Cp*W(NO)Ph₂

Doi:10.1021/om00017a077
(1994)
Design and evaluation of ω-hydroxy fatty acids containing α-GalCer analogues for CD1d-mediated NKT cell activation

Doi:10.1021/ml400517b
(2014)
Preparation of C-1 glycals via olefin metathesis. A convergent and flexible approach to C-glycoside synthesis

Doi:10.1021/jo982331o
(1999)
COMPOUNDS WITH THE LABDANE SKELETON FROM HALIMIUM VISCOSUM

Doi:10.1016/S0031-9422(00)90593-4
(1994)
Hydrosilylation catalysis by an earth alkaline metal silyl: Synthesis, characterization, and reactivity of bis(triphenylsilyl)calcium

Doi:10.1039/c3cc49308c
(2014)

Article Doi