Tandem Radical Cycloaddition. Remarkable Silyl Substituent Effect on the Chemoselectivity of the Radical Cyclization Reactions

Article abstract of DOI:10.1021/jo00073a002

Tandem radical cyclization of bromides 1 with Bu3SnH is extremely sensitive to the nature of the substituent on the diene moiety.Bicyclo<3.1.0> skeleton 3 is obtained in the presence of the silyl substituent.The tert-butyl substituent gives exclusively si