Tetrahedron p. 1967 - 1974 (1994)
Update date:2022-07-29
Topics:
McIntosh, John M.
Thangarasa, Rasiah
Foley, Nancy K.
Ager, David J.
Froen, Diane E.
Klix, Russell C.
Benzylation of chiral esters of N-acyglycines using various bases and additives was examined.No C-alkylation was observed with one equivalent of base.Diastereoselectivities were dependent on the amount of additive, the nature of the N-acyl group, and the chiral ester.A model to account for the degree and sense of the stereoselectivity is proposed.
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Doi:10.1016/j.bmcl.2017.07.054
(2017)Doi:10.1016/S0040-4039(00)61716-1
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(2014)Doi:10.1139/v63-103
(1963)
