A novel synthesis of the 5HT3-receptor antagonist BRL 49231

Article abstract of DOI:10.1080/00397919408011703

A short route to the 5HT₃ receptor antagonist BRL 49231 involving alkylation of the amide enolate of 1-acetyl-3,3-dimethylindoline is described.

Full text of DOI:10.1080/00397919408011703

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A Novel Synthesis of the 5HT3-
Receptor Antagonist BRL 49231
Sandra J. Paknoham a & Martyn Voyle a
a Synthetic Chemistry , SmithKline Beecham
Pharmaceuticals , Coldharbour Road, The Pinnacles,
Harlow, Essex, CM19 5AD, UK
Published online: 23 Sep 2006.
To cite this article: Sandra J. Paknoham & Martyn Voyle (1994) A Novel Synthesis of
the 5HT3-Receptor Antagonist BRL 49231, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 24:8, 1091-1100,
DOI: 10.1080/00397919408011703
To link to this article: http://dx.doi.org/10.1080/00397919408011703
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