Asymmetric synthesis. XXX. Synthesis of 3-substituted piperidines from chiral non-racemic lactams

DOI: 10.1016/S0040-4039(00)77162-0

Source and publish data:

Tetrahedron Letters p. 2529 - 2532 (1994)

Update date:2022-08-03

Topics:

Authors:

Micouin, Laurent

Varea, Teresa

Riche, Claude

Chiaroni, Angele

Quirion, Jean-Charles

Husson, Henri-Philippe

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Article abstract of DOI:10.1016/S0040-4039(00)77162-0

A series of 3-substituted piperidines in enantiomerically pure form has been synthesized from lactam 3 by a stereospecific route involving a postulated rigid amide enolate. This strategy has been applied to the synthesis of (+)-stenusine 10.

Full text of DOI:10.1016/S0040-4039(00)77162-0

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