Dispiroketals in synthesis (part 10): Further reactions of dispoke protected lactate and glycolate enolates

Article abstract of DOI:10.1016/S0040-4020(01)85241-8

α-Hydroxy acids have been reacted with bis-dihydropyrans to give dispiroketal adducts (1,8,13,16-tetraoxadispiro[5.0.5.4]-hexadecan-14-ones). The enolates derived from these compounds undergo reaction with electrophiles with generally high levels of diast