A short asymmetric synthesis of (+)-nonactic acid and (-)-8-epi-nonactic acid induced by a chiral sulfoxide group

Article abstract of DOI:10.1021/jo00093a022

A short enantioselective synthesis of (+)-(2S,3S,6R,8R)-nonactic acid and (-)-(2R,3R,6S,8R)-epinonactic acid is described. The key step was the stepwise stereoselective reduction of the triketo sulfoxide B without any protective group on the different carbonyls.