Organometallics p. 2262 - 2268 (1994)
Update date:2022-08-05
Topics:
Casta?o, Ana M.
Echavarren, Antonio M.
The five-membered nickelacycle derived from aspartic acid by oxidative addition followed by decarbonylation reacts with alkyl iodides and bromides to give α-amino acids, after hydrolysis of the reaction products. Carbonylation products were, however, observed with benzyl or allyl bromide. The involvement of radicals in the alkylation reaction pathway has also been explored. Oxidation of the nickelacycle with N-methylmorpholine N-oxide or dioxygen gave N-protected serine. On the other hand, benzoyl peroxide promoted the insertion of carbon monoxide or isocyanides into the Ni-C bond. Phenylacetylene and 1-octyne also insert into the Ni-C bond of the nickelacycle to give alkenyl or alkynyl products.
View MoreContact:+86-021-50792271
Address:Building 24A, 300 Chuantu Road, Chuansha, Pudong new area, Shanghai, China, 201202
Shanghai Balmxy Pharmaceutical Co., Ltd
Contact:0086-21-24206007
Address:Room 402, 15#, No. 909 wangyue Road, shanghai, P. R. China
Anhui Gusheng Import&Export CO.,LTD
Contact:86-551-63662296
Address:Jinzhai Road NO.162 ,hefei, china
Yangling Ciyuan biotech Co., Ltd.
Contact:86-15802970736
Address:2-1804, International Park Mansion, No.2, South Fengdeng Road, Lianhu District
Shanghai Synmedia Chemical Co., Ltd
Contact:+86-21-38681880
Address:6th Floor, 11A Building, No.528 Ruiqing Road, Heqing town, Pudong new district, Shanghai China
Doi:10.1080/00397919408010194
(1994)Doi:10.1002/anie.201510445
(2016)Doi:10.1021/jo00092a006
(1994)Doi:10.1002/hc.21166
(2014)Doi:10.1039/P19940002363
(1994)Doi:10.1002/adsc.201100737
(2012)