Bioorganic and Medicinal Chemistry Letters p. 295 - 300 (1999)
Update date:2022-08-02
Topics:
Nelson, Frances C.
Stachel, Shawn J.
Eng
Sehgal, Suren N.
A novel series of rapamycin derivatives with modifications in the C(22)- C(27) region has been prepared. These compounds are evaluated for their ability to prevent ring fragmentation while still retaining immunosuppressive capabilities.
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