Journal of Agricultural and Food Chemistry p. 2002 - 2006 (1994)
Update date:2022-08-05
Topics:
Speranza, Giovanna
Corti, Sandra
Manitto, Paolo
The structure of a new constituent of Cape aloe was determined by spectral analysis and confirmed by total synthesis. This 1,1-diphenylethane derivative (6), which occurs in the drug in racemic form, was also obtained by thermal reaction of p-coumaric acid with orsellinic acid (or orcinol). These facts are consistent with a nonenzymatic origin of 6, which can be regarded as the first process product isolated from aloe. Keywords: Cape aloe; secondary metabolites; polyketides; 1,1-diphenylethane derivatives; process product; thermal decarboxylation; p-coumaric acid
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