N-Hydroxymethylnorcotinine, a new primary in vitro metabolite of cotinine

Article abstract of DOI:10.3109/00498259409043244

1. N-Hydroxymethylnorcotinine; 5-(3'-pyridyl)-1-hydroxymethyl-pyrrolidone-2, was found as a new primary metabolite of cotinine in vitro. 2. N-Hydroxymethylnorcotinine was synthesized and characterized by gas chromatography-mass spectrometry, mass spectra, nuclear magnetic resonance and ultraviolet spectroscopy. 3. This new metabolite is formed by incubation of cotinine with hamster hepatic microsomes in the presence of NADPH and oxygen.

Full text of DOI:10.3109/00498259409043244

Xenobiotica
the fate of foreign compounds in biological systems
ISSN: 0049-8254 (Print) 1366-5928 (Online) Journal homepage: http://www.tandfonline.com/loi/ixen20
N-Hydroxymethylnorcotinine, a new primary in
vitro metabolite of cotinine
Y. Li & J. W. Gorrod
To cite this article: Y. Li & J. W. Gorrod (1994) N-Hydroxymethylnorcotinine, a new primary in
vitro metabolite of cotinine, Xenobiotica, 24:5, 409-415, DOI: 10.3109/00498259409043244
To link to this article: http://dx.doi.org/10.3109/00498259409043244
Published online: 22 Sep 2008.
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Date: 16 March 2016, At: 01:31